Description

What is a VHP Pass Box?

A VHP Pass Box is a decontamination chamber used to transfer materials into a cleanroom without introducing contamination. It uses Vaporized Hydrogen Peroxide (VHP) sterilization to eliminate microbial contamination before the material enters the controlled environment.

Where is it Used?

• Pharmaceutical & Biotechnology Cleanrooms – For transferring sterile equipment.
• Hospitals & Healthcare Facilities – Ensures contamination-free material transfer.
• Microelectronics & Semiconductor Industry – Protects components from microbial contamination.

 

Integrated Bio-decontamination System

• Esco Pharma has developed an effective hydrogen peroxide based bio-decontamination system capable of achieving a log 6 reduction in bio-burden. The spore log reduction has been validated by biological indicator challenge using biological indicator stainless steel ribbons populated with Geobacillus Stearothermophilus spores.
• The interior and cleanroom side face is made of 316 L stainless steel with a smooth interior and coved corners to ensure easy cleaning and biodecontamination.The interior surface is polished to 0.6 Ra µm or better and external surfaces exposed to cleanrooms 1.2 Ra um or better. The cleanroom wall interface allows a flush finish with the surface for cleanliness.
• Chamber doors are constructed from FDA compliant materials with integrated FDA approved silicone inflatable seal around the perimeter. Doors shall give >90° opening for full access. The doors are not held closed with a mechanical latch, they are the same as our isolators where the seal locks them closed.
• Direct reading pressure gauges are provided to both sides of the pass through to give indication of the chamber pressure.
• Integrated with Esco BioVAP bio-decontamination system with PLC control, HMI operator interface and ticket roll printer to give hard copy of the bio-decontamination cycle.
• Interlocking doors to prevent opening at the same time and also to prevent the sterile unloading doors from opening until after a bio-decontamination.
• Optional on-board Catalytic Converter to allow air to be taken from the room and exhausted back to room, with interlocked safety exhaust H2O2 sensor. Avoids costly HVAC ducting.

 

How Does It Work?

• Material is placed inside the VHP Pass Box.
• The doors interlock to prevent direct exposure.
• The system injects and circulates VHP gas inside the chamber.
• Hydrogen peroxide sterilizes all surfaces, killing 99.99% of microorganisms.
• After sterilization, the gas is neutralized, and the material is ready for transfer.

 

Specifications:

• Material: SS 304 / SS 316L construction.
• Decontamination System: VHP-based sterilization.
• Filtration System: HEPA filters (99.99% efficiency).
• Door System: Electromagnetic interlocking doors.
• Control Panel: PLC-based touchscreen with sterilization cycle settings.

 

Features:

• 100% Sterilization – Destroys bacteria, viruses, fungi & spores..
• No Residue, No Damage – Safe for pharmaceutical & electronic materials.
• Fully Automated Process – Ensures consistent sterilization cycles.
• Safety Mechanism – Door remains locked until complete sterilization.
• Energy Efficient – Low power consumption with optimized VHP usage.

 

Compliance & Standards:

• CGMP
• ISO 14644
• WHO-GMP
• FDA

 

SERVICE AREA

LOCATION:

VASAI	VAPI	DAMAN	HARIYANA	GOA
ANDHERI	BARAMATI	AHMEDABAD	HARIDWAR	RAJASTHAN
THANE	NASHIK	KOLKATA	SIDDCUL	UDYAPUR
TALOJA	DAHEJ	CHENNAI	SIKKIM	HYDERABAD
PALGHAR	SURAT	BENGALURU	INDORE	TURBHE
BOISAR	VADODARA	BADDI	UTTAR PRADESH	HINJWADI